Yildirim Cinar, Good. Mete Senyol, Kamber Duman, Blood viscosity and you will blood pressure level: part off temperatures and you will hyperglycemia, Western Record out of Blood pressure levels, Volume step 14, Thing 5, best dating hookup apps 2021 , Profiles 433–438,
We planned a study to research the relations among blood pressure (BP), viscosity, and temperature in healthy subjects and among BP, viscosity, and glucose in diabetics. With simple random sampling method, 53 healthy and 29 diabetes mellitus (DM) type II subjects were selected. Parameters were determined with capillary viscometer and glucometer at 22°C, 36.5°C, and 39.5°C in healthy subjects, and at 22°C on diabetic patients during OGTT with 75 g of glucose. Statistical evaluations of the data were made with regression analysis, Student t test, Spearman’s correlation, and analysis of variance. When temperature decreased from 36.5°C to 22°C, blood viscosity increased %. This increase resulted in a % decrease in blood flow rate. According to the Hagen-Poiseuille equation, the required BP increase for compensation of the resulting tissue ischemia was %. Also, a % decrease in erythrocyte deformability and % increase in plasma viscosity were seen. When temperature increased from 36.5° to 39.5°C, blood viscosity decreased %. This caused % decrease in blood flow rate, and % decrease in BP, according to the equation. Erythrocyte deformability increase of 9.92% and plasma viscosity decrease of 4.99% arose from the temperature rise. There is a correlation between total data for temperatures and viscosities (r = ?0.84, P < .001). When the mean value of blood glucose increased from 100 to 400 mg/dL, viscosity increased 25% (r = 0.59, P = .002). In this state, blood flow rate decrease was 20% and BP increase for physiological compensation was 25%. Consequently, temperature, glucose and viscosity levels of blood are important factors for BP. Am J Hypertens 2001;–438 © 2001 American Journal of Hypertension, Ltd. The aim of the study is always to research the matchmaking certainly temperatures, sugar focus, and viscosity of blood and you can plasma, in order to calculate their effects into the blood pressure (BP) considering Hagen-Poiseuille’s hydrodynamics formula. If the human circulatory system is considered as a closed system, hemodynamic equilibrium can be determined according to Poiseuille’s equation through the pressure, viscosity, flow rate, velocity of blood, and vessel diameter. Viscosity can be defined as the resistance of fluids against flow. The resistance for blood circulation includes friction between the blood elements and between the vessel lumen and blood. To make a fluid flow, the application of energy is required. Therefore, the energy of the circulatory system is spent in correlation with the viscosity level of blood. Energy forms of the circulatory system are BP and blood flow velocity. The velocity (v) and pressure of blood flow can be determined with Poiseuille’s equation as v = 1/4?L (F1 ? F2) (a 2 ? r 2 ), and also BP rate (Q) can be expressed from the above equation as Q = ?a 4 /8 ?L (F1 ? F2), where ? is the viscosity of the fluid, F1 and F2 are the initial and the final cross sectional pressures of blood, L is the length, a is the radius of vessel, and r is the distance from the center of the vessel for a flowing particle. 1, 2 Thus, to keep the equilibrium of the equation constant in the circulatory system, BP will increase when viscosity increases. It has been revealed one anywhere between % and % philosophy from hematocrit, the eleven% boost in hematocrit increases bloodstream viscosity by the 20%. In this state, considering Poiseuille’s picture, blood circulation speed minimizes from the %, that could end up in tissues ischemia. To keep the fresh new circulatory program into the harmony (which is, keeping brand new flow rate sufficient and blocking cells ischemia), an excellent 20% boost in BP otherwise 4.66% vasodilation is necessary. 3 not, the human circulatory system is perhaps not an exact closed program, since bloodstream viscosity are going to be altered to the intake out-of dinner or medication. 4–8 While doing so, the effects away from fat as well as certain pills on the blood viscosity and you may hemodynamics like BP had been said. Given that atherosclerotic boats cannot dilate sufficiently just like the a reaction to vasodilator drugs, it has been recommended one to enhanced blood viscosity can only just end up being compensated having a good BP increase in such as for instance circumstances. 9–several In addition to, this new matchmaking certainly one of BP, nightmare, coagulation, circulation speed, and you can blood viscosity had been discussed via the principles regarding hemodynamics. 13, 14Bloodstream viscosity and you can blood pressure level: role out-of temperature and you will hyperglycemia